Ether Dome, Massachusetts General Hospital
Photo: Adam Lenhardt, CC BY-SA 3.0, via Wikimedia Commons

Ether Dome, Massachusetts General Hospital

Ether Dome, Massachusetts General Hospital is a building in Boston, Massachusetts, listed on the National Register of Historic Places on October 15, 1966.

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Access
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Last checked October 31, 2026
Location
Boston, Suffolk County, Massachusetts

National Register listing does not mean a place is open to the public. Parking and accessibility are shown only when verified.

History

The Ether Dome is a surgical operating amphitheater in the Bulfinch Building at Massachusetts General Hospital in Boston, Massachusetts, United States. It served as the hospital's operating room from its opening in 1821 until 1867. It was the site of the first public demonstration of the use of inhaled ether as a surgical anesthetic on October 16, 1846, otherwise known as Ether Day. The Ether Dome event occurred when William Thomas Green Morton, a local dentist, used ether to anesthetize Edward Gilbert Abbott. John Collins Warren, the first dean of Harvard Medical School, then painlessly removed part of a tumor from Abbott's neck. After Warren had finished, and Abbott regained consciousness, Warren asked the patient how he felt. Reportedly, Abbott said, "Feels as if my neck's been scratched". Warren then turned to his medical audience and uttered "Gentlemen, this is no Humbug". This was presumably a reference to the unsuccessful demonstration of nitrous oxide anesthesia by Horace Wells in the same theater the previous year, which was ended by cries of "Humbug!" after the patient groaned with pain.

Excerpt from the Wikipedia article, licensed CC BY-SA 4.0. The official nomination form is linked under Sources.

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